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PI staining

A major role of intracellular GSH is maintaining an optimal redox-potential for normal cellular processes which include activation/inactivation of redox-sensitive proteins, regulation of intracellular pH and potassium, deactivation of toxic substances, and adaptation to various stresses (e.g., oxidative stress, temperature stress, or osmotic stress) [16] [22]

Gohel 2009

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Berberine and curcumin target survivin and STAT3 in gastric cancer cells and synergize actions of standard chemotherapeutic 5-fluorouracil